Patients undergoing colorectal surgery are reported to experience an increased incidence of surgical-site infection with the addition of a gentamicin-collagen sponge enclosed at the surgery site. These findings were recently published in the New England... Continue Reading
Screening Rates Among Older Americans (July 15, 2010)More older Americans are undergoing screening for colon cancer, but the rates for breast cancer screening remain the same, according to a government report released on July 6, 2010.[1] The best “treatment” of cancer is preventing its occurrence in... Continue Reading
Radioembolization plus Fluorouracil Active in Colorectal Cancer Patients with Liver Metastases (July 2, 2010)Radioembolization plus the chemotherapy agent fluorouracil slows cancer progression for colorectal cancer patients whose disease has progressed following prior treatment with chemotherapy and have metastases limited to the liver. These findings were recently... Continue Reading
Potential Role for Oncotype DX Colon Cancer Test in Stage III Cancer (June 10, 2010)The Oncotype DX® colon cancer test, which is currently available for treatment planning in Stage II colon cancer, may also predict recurrence risk in Stage III colon cancer. These results were presented at the 2010 annual meeting of the American Society... Continue Reading
Erbitux Does Not Improve Survival in Stage III Colon Cancer with Normal KRAS (June 8, 2010)The addition of Erbitux® (cetuximab) to standard adjuvant chemotherapy in patients with stage III colon cancer who have normal KRAS gene activity does not improve survival, according to the results of a Phase III study presented at the 2010 annual meeting... Continue Reading
Optimal Outcomes with Vascular Endothelial Growth Factor (VEGF) Inhibitors Require Appropriate Hypertension Assessment, Monitoring, and Management (May 28, 2010)An expert panel provided consensus recommendations for appropriate prevention, surveillance and treatment of hypertension (high blood pressure) in patients treated with vascular endothelial growth factor (VEGF) signaling pathway inhibitors. These recommendations... Continue Reading
Depression May Persist With Metastatic Cancer (May 27, 2010)A substantial number of patients with metastatic cancer may suffer from depression which tends to persist and grow more severe toward the end of life, according to the results of a study published early online in the Journal of Clinical Oncology.[1] While... Continue Reading
Vectibix Improves Outcome of Previously Treated Colorectal Cancer (January 27, 2010)Among patients with previously treated, metastatic colorectal cancer, the addition of the targeted therapy Vectibix® (panitumumab) to chemotherapy delayed cancer progression. This benefit was only observed in patients whose tumors did not contain... Continue Reading
First-line Vectibix Delays Progression of Metastatic Colorectal Cancer (January 27, 2010)Among patients with metastatic colorectal cancer that does not have a mutation in the KRAS gene, initial treatment with a combination of chemotherapy and Vectibix® (panitumumab) delays cancer progression by 1.6 months compared with chemotherapy alone.... Continue Reading
Oncotype DX® Predicts Recurrence Risk in Stage II Colon Cancer (January 22, 2010)Among patients with Stage II colon cancer, use of the newly available Oncotype DX® colon cancer test provides information about the risk of cancer recurrence and may help guide treatment decisions. These results were presented at the 2010 ASCO Gastrointestinal... Continue Reading
Patients undergoing colorectal surgery are reported to experience an increased incidence of surgical-site infection with the addition of a gentamicin-collagen sponge enclosed at the surgery site. These findings were recently published in the New England... Continue Reading
Potential Role for Oncotype DX Colon Cancer Test in Stage III Cancer (June 10, 2010)The Oncotype DX® colon cancer test, which is currently available for treatment planning in Stage II colon cancer, may also predict recurrence risk in Stage III colon cancer. These results were presented at the 2010 annual meeting of the American Society... Continue Reading
Erbitux Does Not Improve Survival in Stage III Colon Cancer with Normal KRAS (June 8, 2010)The addition of Erbitux® (cetuximab) to standard adjuvant chemotherapy in patients with stage III colon cancer who have normal KRAS gene activity does not improve survival, according to the results of a Phase III study presented at the 2010 annual meeting... Continue Reading
Oncotype DX® Predicts Recurrence Risk in Stage II Colon Cancer (January 22, 2010)Among patients with Stage II colon cancer, use of the newly available Oncotype DX® colon cancer test provides information about the risk of cancer recurrence and may help guide treatment decisions. These results were presented at the 2010 ASCO Gastrointestinal... Continue Reading
Physical Activity Improves Survival of Men with Localized Colorectal Cancer (December 23, 2009)Men who report the most physical activity after a diagnosis of non-metastatic colorectal cancer have a lower risk of death than men who report the least activity. These results were published in the Archives of Internal Medicine. There are over 10 million... Continue Reading
More Adjuvant (I-III, A-C) Colon CancerMore older Americans are undergoing screening for colon cancer, but the rates for breast cancer screening remain the same, according to a government report released on July 6, 2010.[1] The best “treatment” of cancer is preventing its occurrence in... Continue Reading
Early Morning Colonoscopies Detect More Polyps (November 11, 2009)Among patients undergoing colonoscopy at a Veteran’s Administration (VA) medical center, a greater number of polyps was detected among patients seen early in the morning than among patients seen later in the day. The reasons for this are uncertain,... Continue Reading
Excess Body Weight Linked with More Than 100,000 New Cancer Diagnoses Each Year in U.S. (November 9, 2009)According to estimates from the American Institute for Cancer Research (AICR), excess body weight may be responsible for more than 100,000 new cancer diagnoses each year in the United States. Excess body weight is increasingly recognized as a risk factor... Continue Reading
Daily Aspirin Prevents Colorectal Cancer in Lynch Syndrome (October 5, 2009)Daily aspirin may prevent the incidence of cancer in individuals who are genetically predisposed to hereditary nonpolyposis colorectal cancer (HNPCC), also known as Lynch Syndrome, according to the results of a study presented September 21, 2009 at Europe’s... Continue Reading
False-positive Results Are Common with Cancer Screening (July 21, 2009)The risk of obtaining a false-positive result from screening for prostate, lung, colorectal, and ovarian cancer is high and becomes cumulatively higher with ongoing screening—after 14 screening tests, the cumulative risk of a false-positive is 60.4%... Continue Reading
More Screening/Prevention Colon CancerRadioembolization plus the chemotherapy agent fluorouracil slows cancer progression for colorectal cancer patients whose disease has progressed following prior treatment with chemotherapy and have metastases limited to the liver. These findings were recently... Continue Reading
Optimal Outcomes with Vascular Endothelial Growth Factor (VEGF) Inhibitors Require Appropriate Hypertension Assessment, Monitoring, and Management (May 28, 2010)An expert panel provided consensus recommendations for appropriate prevention, surveillance and treatment of hypertension (high blood pressure) in patients treated with vascular endothelial growth factor (VEGF) signaling pathway inhibitors. These recommendations... Continue Reading
Depression May Persist With Metastatic Cancer (May 27, 2010)A substantial number of patients with metastatic cancer may suffer from depression which tends to persist and grow more severe toward the end of life, according to the results of a study published early online in the Journal of Clinical Oncology.[1] While... Continue Reading
Vectibix Improves Outcome of Previously Treated Colorectal Cancer (January 27, 2010)Among patients with previously treated, metastatic colorectal cancer, the addition of the targeted therapy Vectibix® (panitumumab) to chemotherapy delayed cancer progression. This benefit was only observed in patients whose tumors did not contain... Continue Reading
First-line Vectibix Delays Progression of Metastatic Colorectal Cancer (January 27, 2010)Among patients with metastatic colorectal cancer that does not have a mutation in the KRAS gene, initial treatment with a combination of chemotherapy and Vectibix® (panitumumab) delays cancer progression by 1.6 months compared with chemotherapy alone.... Continue Reading
More Stage IV (D)/Relapsed Colon Cancer